International Journal of Herbal Medicine
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E-ISSN: 2321-2187, P-ISSN: 2394-0514   |   Impact Factor: RJIF 5.20 NAAS Rating: 3.20
International Journal of Herbal Medicine
Vol. 1, Issue 2, Part A (2013)

Anti-diarrheal activity of Melastoma malabathricum L. leaf extracts (Melastomataceae)

Author(s): Karuppasamy Balamurugan, Antony Nishanthini, Veerabahu Ramasamy Mohan
Abstract: The objective of this study was to investigate the anti-diarrheal activity of leaf of Melastoma malabathricum in rats. Anti-diarrheal effects of the ethanol extracts at 100, 200 and 400 mg/Kg were evaluated in rats using castor oil induced models. Results showed that the ethanol extract exhibited significant and dose dependent anti-diarrhoeal activity in the model used. A percentage diarrheal inhibition of extract at 400 mg/Kg was 93.67%. Diarrheal protection in the model used by the extract is dose dependent and the diarrhoeal inhibitory effects of the extract are comparable to loperemide. Therefore, a result of present study suggests that the ethanol extract ofMelastoma malabathricum possesses anti-diarrheal activity.
Pages: 102-105  |  962 Views  9 Downloads
How to cite this article:
Karuppasamy Balamurugan, Antony Nishanthini, Veerabahu Ramasamy Mohan. Anti-diarrheal activity of Melastoma malabathricum L. leaf extracts (Melastomataceae). International Journal of Herbal Medicine. 2013; 1(2): 102-105.
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International Journal of Herbal Medicine