Author(s): Shaukat Mahmud, Ghazala H. Rizwani, Huma Shareef, Shahnaz Gauhar, Sumaira Ishaq, Rehana Perveen

Abstract: Anti-inflammatory action of ginger has been confirmed by various scientists, but there is very few review article published till date on inflammation associated diseases. Inflammation is mainly, culprit of anemia and inflammation associated disorder (like- Pulmonary diseases, Cardiovascular diseases, Diabetes Type-2, cancer, Arthritis, Alzheimer, Neurological diseases and Autoimmune diseases).Since Infection (bacterial/ viral), activate Nuclear factor –-κB, which is a major mediator of inflammation in most of the disease. Zinger has been established potent NF–ƙB inhibitory action via the suppression of pro-inflammatory cytokine, TNF-α and also provides a molecular link between the innate and adaptive immune system. This review takes the Zinger bioactive components, property, Chemical composition, Mechanism of action, function, side effects, current research and their potential application in modern medicine. The present study demonstrates that ginger showed broad spectrum action in which Anti-inflammatory action is one of them. So the present study concludes that ginger and its bioactive components have the potential for development of modern medicine in the treatment of anemia and various diseases in near future.