Author(s): Sanjay Yadav, Sanjib Das, N. C. Baruah, Mukesh Dubey

Abstract: The selected plant Alternenthera sessilis (L.), Houttuynia cordata(Thunb) Murraya koenigii (L.) and Ziziphus oenoplia (L) Miller has been used traditionally in Assam, India for the treatment of diarrhoea and dysentery. However, the claims need to be validated by a suitable experimental model.  Therefore, the present study was under taken to evaluate the effect of 50% methanol extracts of Alternenthera sessilis (L.) whole plant (ASM), Houttuyniacordata (Thunb) Aerial part (HCM), Murraya koenigii (L.) Leaves (MKM) andZiziphus oenoplia (L) Miller Root Bark (ZOM) for its antidiarrhoeal potential against experimental models of diarrhoea in Albino Wister rats. The plant extracts showed significant (P < 0.05) inhibitor activity against castor oil induced & magnesium sulphate induced diarrhoeain rats. The results point out the possible antidiarrhoeal effect of the plants extract traditionally used in Assam, India.