Vol. 2, Issue 3, Part A (2014)
A study on analgesic activity of Holarrhena antidysenterica leaves
Author(s): Shwetha C, Latha K.P, Asha K
Abstract: The plant Holarrhena antidysenterica commonly known as ‘Kutaja’ belongs to the family Apocynaceae, is a small shrub or small tree evergreen in nature. The plant is medicinally important which is used to cure various diseases like diarrhea, dysentery, piles, biliousness and also with potent antioxidant activity. The analgesic activity of plant Holarrhena antidysentericawas evaluated by using the petroleum ether, chloroform and ethanolic extracts at the dose of 300, 300 and 250 mg/kg body weight respectively in the albino mice. The study was conducted as per the acetic acid induced writhing method. The ethanolic extract showed significant analgesic activity when compared to the standard Aspirin at the dose of 150 mg/kg of body weight. The findings indicated that the ethanolic extract exhibited potent analgesic activity comparable to that of the standard drug.
How to cite this article:
Shwetha C, Latha K.P, Asha K. A study on analgesic activity of Holarrhena antidysenterica leaves. International Journal of Herbal Medicine. 2014; 2(3): 14-16.