Author(s): Pooja Rohilla, Raghavendra Naik and RN Acharya

Abstract: Osteoarthritis is one of the most common degenerative joint disorders. In Ayurveda, the disease Sandhivata resembles with osteoarthritis which is described under Vatavyadhi. Classical texts of Ayurveda, recommends different single herbal remedies for the management of Sandhivata, and many of them are now in routine clinical practice. The present review has been made from different pre-clinical and clinical research works carried out on single herbal drugs for the management of Sandhivata at Dravyaguna department of IPGT&RA, Gujarat Ayurved University, Jamnagar. Analysis of results shows that, about 22 research works comprising of 3 clinical and 19 experimental studies have been conducted by Dravyaguna department of IPGT&RA on Sandhivata. Drugs like seeds of Lepidium sativum Linn, whole parts of Leonotis nepetifolia (L.) and roots of Blepharispermum subsessile DC are found effective clinically, in the management of Sandhivata. Drugs like Bridelia scandens Willd, Paederia foetida Linn. Celastrus paniculatus Willd. , Leonotis nepetifolia (L.) R. Br. are proven experimentally for their anti-arthritic, analgesic and anti-inflammatory activities which are the main line of treatment in osteoarthritis. The findings of present review highlight the use of these single and simple herbal remedies for the treatment of patients suffering from Sandhivata and can give a lead to further extensive research on these drugs.