Author(s): Naresh Kumar Ghodela and Tukaram Dudhamal

Abstract: Healing of wound is a challenging task to surgeon in ancient time and even in today’s era. Healing is protective mechanism of our body to invade against infection. In modern science many antibacterial formulations are available with their own limitations. Ayurveda is a science of medicine where there are so many pieces of pearl available to treat wound without any complication. Our Acharyas broadly described about treatment principles of wound management and classified the drugs related to Vrana shodhana and Vrana ropana. In this article an attempt has been made to review clinically validated evidence based herbal and herbo-mineral formulations. These scientific evidences definitely impact our Ayurveda system too really on them and need keen interest to apply different formulations according to the nature and type of wounds. For that purpose the research articles and case reports were searched in PubMed, DHARA online and AYUSHPORTAL (a research portal of Govt. of India.) in the month of June 2016. Total 536 research papers were found on wound key words but after evaluating each free assess research paper 48 clinical studies while 98 pharmacological studies were found. Free accessible 28 clinical studies till June 2016 were included in this article. This review article is definitely helpful to the new researcher to study on the same plant in more number of patients with different indication for its scientific validation.