Author(s): Nimmy K Francis, Harpreet S Pawar, Nabam Peter, Gaurav Biswas, Jayjeet Majumdar, Anirban Mitra and Analava Mitra

Abstract: Diabetes is a chronic metabolic syndrome characterized by impaired wound healing and secondary wound infections attributing to the economy. The plant Ocimum sanctum (basil) is widely used owing to its chemo-immuno modulatory, antimicrobial and anti-inflammatory characteristics. Study aims to elucidate therapeutic potential of alcoholic extract of basil in wound healing in diabetic rabbit model. Animals were divided into wounded control treated with povidone Iodine and test with basil extract. Semi-quantitative and qualitative evaluation of tissue architecture and immuno-histochemistry encompassing collagen I and III studies expressed swift regeneration of injured epidermis in basil extract treated wound in comparison to control. This is articulated by organized dermal collagen deposition with collagen I to III ratio resembling normal skin, wound area measurement and absence of clinical signs of wound infection. Encouraging primary evidences for swifter wound healing requisites further experimental validation for the translation and standardization of the product from bench to bedside.