International Journal of Herbal Medicine
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E-ISSN: 2321-2187, P-ISSN: 2394-0514   |   Impact Factor: RJIF 5.20 NAAS Rating: 3.20
International Journal of Herbal Medicine
Vol. 5, Issue 5, Part A (2017)

Study on anti- Toxoplasma effects of Myrtus communis andArtemisia aucheri Boiss extracts

Author(s): Farzaneh Javadi, Abbas Azadmehr, Hassan Jahanihashemi, Mohtaram Adineh, Shaghayegh Nozari, Reza Hajiaghaee, Mojtaba Shahnazi and Mehrzad Saraei
Abstract: Achieving an anti- Toxoplasma product with high efficacy and low side effect is a priority in research on Toxoplasma gondii. Herbal products may be a suitable candidate for this purpose. The present study was performed to evaluate anti-Toxoplasma effects of Myrtus communis and Artemisia aucheri Boiss extracts in vitro. T. gondii RH strain tachyzoites were exposed to extracts of M. communis and A. aucheri Boiss both in cell-free medium and cell culture. Mortality rate of tachyzoites and EC50 of the extracts were calculated. The results were analyzed with one way ANOVA, followed by Tukey's HSD using SPSS software. Both extracts demonstrated cidal effects on tachyzoites in cell-free medium. But, in cell culture, EC50 and selectivity of M. communis and A. aucheri Boiss were significantly lower than pyrimethamine. M. communis and A. aucheri Boiss extract failed to act as a good alternative to synthetic anti-Toxoplasma drugs.
Pages: 16-19  |  815 Views  20 Downloads
How to cite this article:
Farzaneh Javadi, Abbas Azadmehr, Hassan Jahanihashemi, Mohtaram Adineh, Shaghayegh Nozari, Reza Hajiaghaee, Mojtaba Shahnazi and Mehrzad Saraei. Study on anti- Toxoplasma effects of Myrtus communis andArtemisia aucheri Boiss extracts. International Journal of Herbal Medicine. 2017; 5(5): 16-19.
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International Journal of Herbal Medicine