Author(s): Amit Bhatt, Geeti Sood and CP Kashyap

Abstract: Prameha is a common disease encountered by clinicians in daily practice. It is mainly characterized by polyuria and turbid urine. A number of formulations are described in Ayurvedic literature for management of Prameha. To establish a reliable therapeutic module, a clinical trial was carried out to evaluate therapeutic efficacy of Vang Bhasma with Shuddha Shilajatu and Vang Bhasma with Guduchi Satva in relief in symptoms of Prameha and also to compare the effect of both drugs. It was open randomized comparative clinical study with pre and posttest design. 20 patients were diagnosed as suffering from Prameha. These patients were randomly divided into 2 groups of 10 patients each. 10 patients were treated with Vang Bhasma with Shuddha Shilajatu and 10 patients were treated with Vang Bhasma with Guduchi Satva for 30 days. They were evaluated on subjective parameters like Prabhuta mutrata, Pipasa, Kshudha, Klama, Karapada daha, Karapada suptata, Pindiko udveshtana, Mukha shosha and Sandhi shoola. Fasting and Post prandial blood sugar level of each patient was also observed. There was marked relief in symptoms of Prameha in patients of both groups as evidenced by reduction in the mean score of various subjective parameters and laboratory investigations. There was statistically highly significant result in most of the subjective parameters, but while comparing both the groups, there was insignificant difference in the results. Thus it can be stated that Vang Bhasma with Shuddha Shilajatu and Vang Bhasma with Guduchi Satva both therapeutic modules are effective in relieving symptoms of Prameha as evidenced by statistically significant reduction in the symptom score of various subjective and objective parameters.