Vol. 6, Issue 2, Part B (2018)
Quantitative identification of total silymarin in wild Silybum marianum L. by using HPLC
Author(s): Ghaleb Tayoub, Huda Sulaiman and Malik ALorfi
Abstract: Silymarin, a mixture of flavonolignans exhibiting many pharmacological activities, is obtained from the fruits of milk thistle (Silybum marianum L. Gaertner). In this study, we measured the levels of total silymarin in the seeds of Silybum marianum from four different locations in Syria. Using high performance liquid chromatography. Results showed that, Silymarin concentrations varied according to the geographical location. Total silymarin concentrations in seeds ranged between 0.54 % and 2.91% dry weight. Significant differences in silymarin concentrations were found between various sampling locations as determined by LSD test at P<0.05. The highest concentrations of silymarin were in the seeds collected from Damascus (2.91%), and the lowest concentrations were found in seeds obtained from Homs (0.54%). seeds collected from Tartus and Lattakia contained (1.27%) and (1.39%) silymarin respectively. The S. marianum seeds is a cheap and wealthy source of silymarin in Syria.
How to cite this article:
Ghaleb Tayoub, Huda Sulaiman and Malik ALorfi. Quantitative identification of total silymarin in wild Silybum marianum L. by using HPLC. International Journal of Herbal Medicine. 2018; 6(2): 110-114.