International Journal of Herbal Medicine
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E-ISSN: 2321-2187, P-ISSN: 2394-0514   |   Impact Factor: RJIF 5.20 NAAS Rating: 3.20
International Journal of Herbal Medicine
Vol. 1, Issue 3, Part A (2013)

Anti-inflammatory Activity of Characterized Compound Diosgenin Isolated from Tinospora malabarica Miers in Ann. (Menispermaceae) in Animal Model

Author(s): D. Punitha, M. R.Udhayasankar, U. Danya, K. Arumugasamy, A. Shalimol
Abstract: At concentrations of diosgenin isolated from Tinospora malabaricawas investigated in chemically-induced inflammation rodents’ model. It showed a significantly (P < 0.01) reduced mean paw edema volume at 3h after carrageenan injection. These extracts have exhibited anti-inflammatory activity in a dose-dependent manner with the per cent inhibition of paw edema, as compared with the control group. This result indicated that the characterized compound, diosgenin at the dose of 400µg/kg.b.wt showed a maximum anti-inflammatory activity of 82.25% as compared to the reference drug, indomethacin (82.01%). Therefore, our studies support the use of active constituents from T. malabarica in treating inflammations.
Pages: 76-78  |  965 Views  5 Downloads
How to cite this article:
D. Punitha, M. R.Udhayasankar, U. Danya, K. Arumugasamy, A. Shalimol. Anti-inflammatory Activity of Characterized Compound Diosgenin Isolated from Tinospora malabarica Miers in Ann. (Menispermaceae) in Animal Model. Int J Herb Med 2013;1(3):76-78.
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International Journal of Herbal Medicine