Author(s): Omari Amuka, Paul Okemo, Alex Machocho, Paul Mbugua Eliud NM Njagi and Anthony Nyamache

Abstract: This article reviews literature related to the study. It focuses on the historical use of plants as medicine by human. The approach taken is based on the geographical location of various civilizations in which the plants are/were used as source remedies throughout the five continents of the world. Topical issues and an overview cover on medicinal plants, past and their present uses, use of antibiotics in allopathic medicine and development of antimicrobial and antifungal resistance drugs to the currently use. In addition, issues on the emergence and reemergence of new and old diseases have also been covered.