Vol. 4, Issue 4, Part B (2016)
Antidiarrhoeal evaluation of traditionally used Ziziphus oenoplia (L.) Mill root
Author(s): Sanjay Yadav, Sanjib Das, SK Ghosh and NP Yadav
Abstract: Ziziphus oenoplia (L.) Mill. (Z. oenoplia) (Family-Rhamnaceae) is an annual herb that is used in the traditional medicine of Iran for treating stomach and intestinal disorders. In order to collect ethnobotanical information about antidiarrhoeal plants, we performed inquiries among traditional healers, were designated as having antidysenteric and antidiarrhoeal properties. They were found to contain alkaloids, tannins, saponins, sterols and/or triterpenes and reducing sugars. This study evaluates the potential antidiarrhoeal activity of “methanol extract of Z. oenoplia root" (ZOM) in experimental diarrhoea, induced by castor oil and magnesium sulphate in rat at 200 and 400 mg/kg b.w. Both doses were given orally, showed significant antidiarrhoeal activity comparable with that of the standard drug loperamide. On the basis of these ﬁndings, it can be assumed that Z. oenoplia could be a potential source for novel discovery for antidiarrhoeal. These results may support the fact that this plant is used traditionally to cure diarrhoea.
How to cite this article:
Sanjay Yadav, Sanjib Das, SK Ghosh, NP Yadav. Antidiarrhoeal evaluation of traditionally used Ziziphus oenoplia (L.) Mill root. Int J Herb Med 2016;4(4):98-102.