Vol. 5, Issue 6, Part A (2017)
Evaluation of wound healing activity in streptozotocin induced diabetic rats by ethanolic extract of Blepharis maderaspatensis (L.) B. Heyne ex Roth
Author(s): Jessy Jacob, NA Aleykutty and Jyoti Harindran
Abstract: Wound healing is a complex process delayed by metabolic disorders like diabetic mellitus,it remains a crippling global health problem today leading to amputation of limbs and digits. Blepharis maderaspatensis (L.) B.Heyne ex Roth is said to be used for wound healing in many ethanobotanical studies. So, it was decided to check the efficacy of the same on streptozotocin induced diabetic rats. The extract was formulated as given in the literature by formulating a paste with 10gs, 15gs, 20gs of extract and 60gs black gram powder which was mixed with egg white and 2 or 3 drops of lime juice q.s. The wound healing efficiency by different concentrations of the extract was monitored by the excision wound healing method. The healing with the standard Framycetin Sulphate 1%w/w was taken as the positive control. The wound was completely healed by the 18th day in the 20% extract while it took 20 days for complete healing in positive control and 23 days for complete healing in negative control. Thereby confirming the reports in the ethanobotanical studies with regard to the wound healing activity of the plant.
How to cite this article:
Jessy Jacob, NA Aleykutty, Jyoti Harindran. Evaluation of wound healing activity in streptozotocin induced diabetic rats by ethanolic extract of Blepharis maderaspatensis (L.) B. Heyne ex Roth. Int J Herb Med 2017;5(6):45-47.