International Journal of Herbal Medicine
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
E-ISSN: 2321-2187, P-ISSN: 2394-0514   |   Impact Factor: RJIF 5.20 NAAS Rating: 3.20
International Journal of Herbal Medicine
Vol. 8, Issue 3, Part B (2020)

Effect of Jatiphala (Myristica fragrans houtt.) in experimentally induced allergic asthma in male wistar Rats

Author(s): Sonali R Menthe, Giridhar Vedantam, Santosh patil and Ravichandra M
Abstract: Several drugs are mentioned in Ayurveda for anti-asthmatic properties under the term shwasahara. Jatiphala (Myristica fragrans Houtt.) is a unique speice explained by acharyas for the treatment of various disorders including shwasa (Asthma), Kasa (Cough), Atisaara (Diarrhoea) etc. In present study, Jatiphala was tried for its effect on experimentally induced allergic asthma in male wistar rats. Jatiphala was collected & subjected to fine powder. Rats were grouped in three groups & sensitized with intraperitoneal ovalbumin (OVA) & aluminium hydroxide & then challenged with OVA – PBS (phosphate buffer solution) aerosols. The blood parameters like TC, DC, AEC, Serum IgE & BALF cellular differential count was measured along with histological analysis of lung. Jatiphala group significantly reduced the eosinophil count in blood, IgE, AEC and number of inflammatory cells in BALF & lung tissues. Results revealed that Jatiphala may have an anti-inflammatory and anti-asthmatic effect on allergic bronchial asthma
Pages: 90-96  |  128 Views  29 Downloads
How to cite this article:
Sonali R Menthe, Giridhar Vedantam, Santosh patil, Ravichandra M. Effect of Jatiphala (Myristica fragrans houtt.) in experimentally induced allergic asthma in male wistar Rats. Int J Herb Med 2020;8(3):90-96.
Call for book chapter
Journals List Click Here Research Journals Research Journals
International Journal of Herbal Medicine