Author(s): Kyoung Sik Park

Abstract: Aucubin, aniridoid glycoside present in Aucuba japonica, Eucommiaulmoides, and Plantagoasiatica, has been reported toshow a wide range of pharmacological activities. The present study is aimed to provide a comprehensive overview of anti-inflammatory activities of aucubin. Peer-reviewed articles on potent anti-inflammatory effects of aucub in were acquired from Pubmed, Scopus, ScienceDirect, and Sci Finder. This review provides a comprehensive advance on the pharmacological studies to confirm the potent anti-inflammatory effect and its underlying molecular mechanism of aucubin. Although a several of in vitro and in vivo researches have demonstrated anti-inflammatory activities of aucubin, further intensive clinical studies are required to confirm its efficacy for treating inflammatory diseases as a therapeutic agent.