Author(s): Sabha Shafi, Ansar Ahmad, Mudasir Khazir, Afsahul Kalam and Mohammad Iqbal Zargar

Abstract: Sharbat-unnab is a liquid dosage form sweet in taste, prepared from the aqueous extract of Unnab (Ziziphus jujuba fruit), being prescribed in various types of fevers, skin diseases and for detoxification and pacification of blood in case of many infective and non-infective disorders. Plant derived antibiotics may be a possible alternative to modern antibiotics and at the same time can minimize the economic constrain of the hectic process of drug development. The ingredients of the test compound were procured from authentic dealer by Regional Research Institute of Unani Medicine (RRIUM) Srinagar. The extract was dissolved in DMSO₄ and subject to antimicrobial evaluation at the department of Pharmaceutical Sciences University of Kashmir. Results obtained in the present study showed that the test drug possesses promising antimicrobial activity against the selected microbes. The zone of inhibition of the test drug against the S. Typhi was highest (32milimeters) and good against E. Coli (20mm).As the antibacterial activity of the test drug was promising, it may validate the classical claims about use of this drug in case of various infective conditions and further studies are mandated.