At present due to change in lifestyle, lot of stress and over nutrition are important causative factors of diabetes mellitus. Prevalence rate of diabetes mellitus in India was 11.8% over the age group of 50 years and that of below 50 years was6.5% and pre diabetics was 5.7%. Diabetic foot ulcer is the most typical complication of diabetes mellitus with a poor prognosis due to micro and macro vascular change as a result of an uncontrolled sugar level. Ayurveda has considered diabetic foot ulcers as dusht vran due to the presence of foul smelling lesions and non-healing nature of the wound. The management of diabetic foot ulcers includes blood sugar level control, antibiotics, debridement of wound and proper wound care. Present case report deals with a 39 year old female patient newly diagnosed case of diabetes mellitus having fluid filled lesions and wound at plantar surface of right foot. This wound is managed on ayurvedic medicines and wound get healed completely ayurveda this wound is considered as dushta vran and Acharya sushruta has mentioned Shashti upkram for the management of wound and preventing the part affected from surgical intervention like amputation which is hampering the daily activities of life.