International Journal of Herbal Medicine
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
P-ISSN: 2394-0514, E-ISSN: 2321-2187   |   Impact Factor: RJIF 5.20
International Journal of Herbal Medicine
Vol. 11, Issue 5, Part C (2023)

Evaluation of hepatoprotective activity of ethanolic extract of Butea monosperma against thioacetamide induced hepatotoxicity in rats

Author(s): Shaikh A, Bhandirge S, Khan A and Gawande A
Abstract: Due to damage of Hepatic tissue, there may impairment in liver function which may have deleterious effect on human health. Management of liver diseases by using natural herb is recent need. In this research we evaluated the hepatoprotective activity of ethanolic extract of SBBM against TTA induced hepatotoxicity in rats. (Group I received 0.1% CMC, Group II received only TTA, Group III received sily marin, Group IV received ethanolic extract of SBBM orally 200 mg/kg &Group V received ethanolic extract of SBBM orally 400 mg/kg)Group II-V received intraperitonial injection of TAA. On 16th day of the experimental period, animals were sacrificed, the serum was separated for the estimations of histopathalogical, biochemical& morphological parameters, results suggest that it may contribute to the chemopreventive effect of SBBM showed a significant recovery in the level of glutathione and its metabolizing enzyme in the liver, which is shown by the elevated levels of SGOT, SGPT, GSH and Lipid peroxidation, Hence, on the basis of result obtained it can be said that SBBM exercised powerful free radical scavenging activity and hepatoprotective activity.
Pages: 187-190  |  195 Views  63 Downloads


International Journal of Herbal Medicine
How to cite this article:
Shaikh A, Bhandirge S, Khan A, Gawande A. Evaluation of hepatoprotective activity of ethanolic extract of Butea monosperma against thioacetamide induced hepatotoxicity in rats. Int J Herb Med 2023;11(5):187-190.

Call for book chapter
Journals List Click Here Research Journals Research Journals
International Journal of Herbal Medicine