From the very beginning, humans have been searching for medicines to maintain their good health and for the treatment of various diseases. The world's largest population uses drugs produced from natural sources. Ginseng is most studied medicinal herb which has long been traditionally used in Asian countries to treat various diseases. The pharmacological activities of ginseng and its constituent’s i.e. ginsenosides are well established.

The conversion of these ginsenosides into smaller compounds through fermentation improves its pharmacological activities, potency and bioavailability. The objective of this article is to summarize the pharmacological activities of fermented ginseng through literature searched from PubMed, PubMed Central, and Google Scholar of articles. To the best of our knowledge, this is the first report for summarization of pharmacological properties of fermented ginseng. In conclusion, it is high time to upgrade the scientific research by adopting various techniques like fermentation to achieve more potent, efficacious and bioavailable drug from the potential herb of Indian origin.