Author(s): Aparajitha N, Sindhu R, Sowndarya Madugula, Lubna Fathima, Indira N, Prabu D, Rajmohan M and Dinesh Dhamodhar

Abstract: Cancer is the second largest cause of death and the burden of cancer as well as cancer therapy on physical and mental health is ever increasing. The adverse effects of cancer chemotherapeutic agents are worsening the quality of life of cancer patients. Also, the availability of chemopreventive agents that have anti-cancer properties is scarce. Hence the research on such agents, derived from natural products with minimal side effects is invaluable. The present study is aimed at exploring the anti-cancer effects of Tacca chintreiri plant. We followed PRISMA guidelines to conduct the systematic review that included a total of 10 experimental studies. The present study indicated that Taccalonolides, Evelynin, Taccachatrone, Chantriolides, Spirostanol saponins, Diarylheptanoids, Diarylheptanoid Glucosides derived from the roots of Tacca chintreiri were found to have anti-cancer effects against human cancer cell lines. These compounds need to be further tested in clinical trials to evaluate and establish the anti-caner effects.

DOI: 10.22271/flora.2025.v13.i4a.997