Author(s): Umesh S Saware, Supriya S Barewar, Ravindra L Bakal, Pooja R Hatwar, Nagesh G Khansole and Niranjan D Waghmare

Abstract: The cyclic vomiting illness known as cannabinoid hyperemesis syndrome (CHS) is linked to cannabis consumption. Our goal is to compile the information that is currently accessible on the pathogenesis, diagnosis, and therapy of CHS. After being first reported in 2004, cannabinoid hyperemesis syndrome (CHS) is still a clinical condition that affects chronic heavy marijuana users but is not well understood. Treatment for the hyper emetic phase includes supportive therapy, fluid resuscitation, and antiemetic medicines; this phase usually ends in 48 hours. Individuals frequently exhibit the acquired habit of taking frequent hot baths, which results in a brief improvement in nausea, vomiting, and abdominal pain. Furthermore, research on humans and animals indicates that prolonged cannabis use may be necessary for the degree of emesis rather than being a requirement for the induction of vomiting.

DOI: 10.22271/flora.2025.v13.i4b.1003