Vol. 4, Issue 6, Part B (2016)
GC-MS Analysis of bioactive components on the leaves extract of Artocarpus hirsutus: A potential folklore medicinal plant
Author(s): Jitendra Patel, Venkateshwar Reddy, GS Kumar, D Satyasai and Shiva Krishna
Abstract: Background: Artocarpus hirsutus belongs to the family Moraceae and this comprises 50 varieties of species. They are deciduous and evergreen tall tree grows up to 75 meters in height in southern regions of India. Objective: The primary objective of this study was to investigate the bioactive constituents from (MEAH) methanolic extract of Artocarpus hirsutus leaves using (GC-MS) Gas Chromatography and Mass Spectroscopy. Material and methods: The methanolic extract obtained was subjected to GC-MS for the determination of bioactive volatile compounds. GC-MS analysis was carried out using 6890 GC with 5973 I MSD Column. Helium was used as the carrier gas, the temperature programming was set with initial oven temperature at 400C and held for 3 min, and the final temperature of the oven was 4800C with rate at 100C. A 2-μl sample was injected with split less mode. Mass spectra was recorded over 35-650 amu range with electron impact ionization energy 70 eV. The total running time for a sample is 20 min. Results: The GC-MS analysis of the methanolic extract revealed the presence of 18 bioactive compounds with valuable biological activities. The major chemical constituents are Butanal, 3-methyl; 2-Methylbutyraldehyde; 2-Methyl-3-propyloxirane; 2-Furancarboxaldehyde 5-methyl-; Propylphosphonic dichloride; 5-Hydroxymethylfurfural; 3,3-Dimethylbutan-2-yl methylphosphonofluoridate; N-PENTADECANE; 2,6-dimethoxy-4-vinyl phenol; Quinic acid; 5,6-Dimethoxy-2-methyl-1-indanone; and n- Hexadecanoic acid. Conclusion: The presence of various bioactive compounds in A. hirsutus proved that the pharmaceutical importance. It can be concluded that the plants investigation have opened up a new perspective in pharmaceutical research and they can be used for the development of potential, novel antioxidant agents for the treatment of many diseases.
How to cite this article:
Jitendra Patel, Venkateshwar Reddy, GS Kumar, D Satyasai and Shiva Krishna. GC-MS Analysis of bioactive components on the leaves extract of Artocarpus hirsutus: A potential folklore medicinal plant. International Journal of Herbal Medicine. 2016; 4(6): 95-97.